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IFNAR2 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 10522-1-AP-20UL
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Beschreibung
The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.Spezifikation
IFNAR2 | |
Polyclonal | |
Unconjugated | |
IFNAR2 | |
IFN alpha REC, IFN alpha/beta receptor 2, IFN R, IFN R 2, IFNABR, IFNAR2, IFNARB, Type I interferon receptor 2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
3455 | |
-20°C | |
Liquid |
Flow Cytometry, Western Blot | |
0.15 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P48551 | |
IFNAR2 | |
IFNAR2 Fusion Protein Ag0191 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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