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BMI1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 10832-1-AP-20UL
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Beschreibung
The antibody 10832-1-AP detected proteins of 45-48 kDa, which may include phosphorylated isoforms of the protein.
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ′Lys-119′, rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.Spezifikation
BMI1 | |
Polyclonal | |
Unconjugated | |
BMI1 | |
BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
12151, 648 | |
-20°C | |
Liquid |
Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot | |
0.27 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P25916, P35226 | |
BMI1 | |
BMI1 Fusion Protein Ag1286 | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |
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